Assessing the optimal strategy for dual antiplatelet therapy
نویسندگان
چکیده
منابع مشابه
A New Strategy for Discontinuation of Dual Antiplatelet Therapy
Methods We randomly assigned 2,117 patients with coronary artery stenosis into 2 groups according to DAPT duration and stent type: 3-month DAPT following Endeavor zotarolimus-eluting stent (E-ZES) implantation (E-ZES 3-month DAPT, n 1,059) versus 12-month DAPT following the other DES implantation (standard therapy, n 1,058). We hypothesized that the E-ZES 3-month DAPT would be noninferior to th...
متن کاملDual antiplatelet therapy: optimal timing, management, and duration.
Platelet activation and aggregability play a key role in the genesis of arterial thrombus secondary to plaque rupture. For coronary patients, inhibition of platelet function is crucial to decrease the rate of major adverse cardiac events but may expose them to excess bleeding risk. Switching P2Y12 inhibitors is common, yet the clinical consequences are unknown. The aim of this review is to prov...
متن کاملDual antiplatelet therapy for heart disease.
Dual Antiplatelet Therapy for Heart Disease Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2014 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.113.004305 2014;129:e506-e508 Circulation. http://circ.ahajournals.org/content/129/21/e506 World Wide Web a...
متن کاملA new strategy for discontinuation of dual antiplatelet therapy: the RESET Trial (REal Safety and Efficacy of 3-month dual antiplatelet Therapy following Endeavor zotarolimus-eluting stent implantation).
OBJECTIVES The goal of this study was to evaluate shorter duration (3 months) dual antiplatelet therapy (DAPT) after drug-eluting stent (DES) implantation. BACKGROUND There have been few published reports of prospective randomized clinical studies comparing the safety and efficacy of shorter duration DAPT after DES implantation. METHODS We randomly assigned 2,117 patients with coronary arte...
متن کاملImpact of Optimal Medical Therapy in the Dual Antiplatelet Therapy Study.
BACKGROUND Continued dual antiplatelet therapy and optimal medical therapy (OMT) improve outcomes in selected patient populations with established coronary heart disease, but whether OMT modifies the treatment effect of dual antiplatelet therapy is unknown. METHODS The DAPT (Dual Antiplatelet Therapy) Study, a double-blind trial, randomly assigned 11 648 patients who had undergone coronary st...
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ژورنال
عنوان ژورنال: Expert Review of Cardiovascular Therapy
سال: 2015
ISSN: 1477-9072,1744-8344
DOI: 10.1586/14779072.2015.1073588